How does Sickle Cell Trait affect your children?

If you are a carrier of sickle cell (Hb AS) and your partner does not carry any haemoglobin disorder (HbAA) there is no particular problem for your child.

In each pregnancy there are two possibilities:

The child may not carry any haemoglobin disorder (Hb AA).

The child may inherit sickle cell trait (Hb AS). This is harmless.

If both you and your partner carry sickle cell (Hb AS) then there is a chance that you could have a child with sickle cell anaemia (Hb SS).

In each pregnancy there are three possibilities:

The child may not carry any haemoglobin disorder (Hb AA). 25% chance.

The child may inherit sickle cell trair (Hb AS). 50% chance. This is harmless.

The child may inherit haemoglobin S from both parents. This child would have sickle cell anaemia (Hb SS). 25% chance.

 

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This is why it is important to find out whether or not you partner is a carrier, before you have a family so that any risk can be discussed.